Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. If your symptoms sound severe, you’ll likely be advised to go to the local hospital for immediate treatment. If you’re unsure of whether you need treatment, call Poison Control at 80 and describe your symptoms. Home treatment may not always accelerate your body’s metabolism of the caffeine. You may also receive breathing support when necessary. Your doctor will likely choose the method that works fastest to get the caffeine out of your body.ĭuring this time, your heart will be monitored through an EKG ( electrocardiogram). A gastric lavage involves using a tube to wash the contents out of your stomach. If the caffeine has already entered your gastrointestinal tract, you may be offered a laxative or even a gastric lavage. You may be given activated charcoal, a common remedy for drug overdose, which often prevents the caffeine from going into the gastrointestinal tract. Treatment is meant to get the caffeine out of your body while managing the symptoms. If you or a child under your care is experiencing these symptoms, seek a doctor’s help immediately for diagnosis and treatment. More serious signs of caffeine overdose can accompany these symptoms, including vomiting, rapid breathing, and shock. Some mild symptoms include nausea and muscles that continually tense and then relax. This can happen when breast milk contains excessive amounts of caffeine. These more serious symptoms of caffeine overdose include:īabies can also suffer from caffeine overdose. Other symptoms are more severe and call for immediate medical treatment. Some symptoms may not immediately alert you that you’ve had too much caffeine because they may not seem serious. Several types of symptoms occur with this condition. What are the symptoms of caffeine overdose? This wide range in average half-life makes it difficult to know the exact amount of caffeine that can lead to overdose. This means it can take anywhere from 1.5 to 9.5 hours for the level of caffeine in your blood to drop to half of its original amount. The average half-life of caffeine in the blood ranges from 1.5 to 9.5 hours. However, what constitutes a safe amount of caffeine differs for everyone based on age, weight, and overall health. Pregnant women should limit their daily intake to less than 200 mg of caffeine per day, since the effects of caffeine on the baby are not fully known. Caffeine overdose may occur if you ingest more than this amount.Īdolescents should limit themselves to no more than 100 mg of caffeine per day. Some of the most popular beverages in the United States, such as coffee, tea, and soda, contain significant amounts of caffeine.Īccording to the Mayo Clinic, the recommended amount of caffeine is up to 400 milligrams per day for healthy adults. It’s commonly used to keep you awake and alert. Graphical abstract.Īntioxidants Chelators Flavonoids Oxidative stress Toxicity.Caffeine is a stimulant found in various foods, drinks, and other products. Prevention is better than cure and thus adding plentiful vegetables and fruits to our diet can combat HM toxicity-related illness. Natural compounds are abundantly available, economic, and have minimal side effects when compared with classical chelators. Natural antioxidants are bestowed with scavenging and chelation properties and can be alternative for synthetic chelating agents. Synthetic chelators impart a major drawback of removing essential metals required for normal body function, along with the toxic one. Natural antidotes, fruits and vegetables, rich in antioxidant are the answers to such toxicities. Toxicity owing to such metals needs prevention rather than therapy. Various databases such as PubMed, Embase, and Science Direct were searched for available facts on natural antidotes and their commercial products against HM toxicity till date. This review gives insights into natural antidotes for the management and prevention of HM toxicity. Toxicity due to heavy metals (HM), specifically mercury (Hg), arsenic (As), lead (Pb), and cadmium (Cd) remains a challenge to scientists till date.
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